About

"The study of evolution is the study of ourselves, our origins, and the very nature of life itself."
— Richard Dawkins

I am Rohan Nath, a PhD student at the Indian Institute of Science Education and Research (IISER) Berhampur, currently pursuing an integrated MS-PhD in the Comparative and Evolutionary Genomics Laboratory under the supervision of Dr. Arunkumar Krishnan. My research focuses on the evolution, pharmacology, and pharmacogenomics of G protein-coupled receptors (GPCRs), with the broader goal of advancing personalized approaches to drug design.

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Portrait of Rohan Nath

Research

Comparative & Evolutionary Genomics
Comparing genomic features across organisms to understand evolutionary relationships, conserved genes, and regulatory elements that illuminate how life diversifies over time.
Genomics · Evolution
Pharmacogenomics
Studying how genetic variation shapes individual drug response, with the aim of optimising therapeutic efficacy and minimising adverse effects through personalized medicine.
Drug Response · Precision Medicine
Structural Biology
Investigating three-dimensional molecular structures to understand biological function and design targeted therapies — particularly for G protein-coupled receptors (GPCRs).
GPCRs · Drug Design
Phylogenomics
Using genome-scale data to reconstruct evolutionary relationships among species, resolving complex phylogenetic histories and the genetic basis of adaptation.
Phylogeny · Adaptation

Publications

2026

Dani, R., Kurbah, I., Chaurasiya, D. K., Nath, R., Krishnan, A., Fushman, D., & Naganathan, A. N. (2026). Selective control of ligand binding through a distal mutation that alters the protein native ensemble. Proceedings of the National Academy of Sciences, 123(8), e2519658123.

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Proceedings of the National Academy of Sciences

2025

Nath, R., Panda, B., Rakesh, S., & Krishnan, A. (2025). Lineage-Specific Class-A GPCR Dynamics Reflect Diverse Chemosensory Adaptations in Lophotrochozoa. Molecular Biology and Evolution, 42(3), msaf042.

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Molecular Biology and Evolution

Contact

Email: rohann20[at]iiserbpr[dot]ac[dot]in  |  rohan[dot]nath[dot]work[at]gmail[dot]com

Address: Indian Institute of Science Education and Research (Permanent Campus), Laudigam, Village Road, Brahmapur, Odisha 760003

Office Location

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